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Benign Prostatic Hypertrophy BPH
Benign Hypertrophy of the Prostate
- BHP

What is BPH?
Causes of BPH
Symptoms of BPH
Complications of BPH
Diagnosing BPH
Treatment of BPH

 
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What is BPH?
The PROSTATE is a small gland at the outlet of the bladder, forming a ring around the URETHRA which is the tube from the bladder to the outside, exiting at the penis. The prostate contributes to semen. PSA which is one of the proteins produced by the prostate keeps semen liquid.  The prostate is inclined to enlarge with age.
 
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Causes of BPH.
Age: The prostate enlarges with age and starts to produce symptoms in men usually after the age of 50.
Race: Asiatic races are less lilkely to develop BPH, caucasians more likely. There is probably an association with diet so this may not be purely genetic.
Diet: vegetarians are less likely to develop BPH, men who eat red meat and drink cows milk are more likely. Soy-based Asiatic diets are associated with less BPH.
 
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Symptoms of BPH result from its position at the neck of the bladder. When the prostate enlarges it presses on the urethra and makes it harder for urine to pass. The early symptoms result from this:
  • poor urine stream: a man will notice his urine does not pass in its previous volume:
  • frequency: he will have to go to the washroom more often because the bladder does not emty completely:
  • hesitancy: a man may have to wait longer to start urinating even though he feels the need to go: eventually he may have to make several trips before succeeding in passing urine.
  • nocturia: he will have to arise more often at night for the same reason.
  • dribbling.
As the condition progresses, symptoms will arise from the complications of BPH:
  • frequency and pain on passing urine from bladder infection. The bladder is prone to infection if it does not empty completely:
  • blood in the urine. This may be a symptom of infection but may also be caued by bladder stones. The salts in the residual urine in the bladder can crystalize out forming small particles, "sand, gravel", and later stones. These irritate the bladder and cause bleeding.
 
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Complications of BPH arise from the blockage it causes on the bladder.
  • UTI - urinary tract infection, first in the bladder, later in the kidneys.
  • Stones - Urine which lies around in the bladder salts out its minerals as sand and gravel particles which eventually form stones.
  • BPH does not cause PROSTATE CANCER.
 
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Basic tests:
Diagnosing BPH is done primarily by history (see symptoms) and clinical examination.
DRE (digital rectal examination) may make the diagnosis if the doctor feels a smoothly enlarged prostate. If it is lumpy the doctor has to rule out cancer.
Urinalysis: to rule out infections and other diseases of the urinary tract.
History, Symptoms, DRE, Urinalysis may be all your doctoer does to make this diagnosis.


Other tests:
PSA
is a protein released by the prostate. It rises with age, with size of prostate and in the presence of cancer of the prostate. Once the doctor feels an enlargement cancer of the prostate has to be ruled out. If the PSA is unduly elevated the doctor will order further investigations. The doctor may order seleted PSA which more acurately helps with diagnosis and with guaging response to treatment.
Prostate ultrasound is a good test for checking the size of the prostate. The big drawback is that ultrasound turns up echoes in the prostate which could be cancer but mostly are not: so many men will have further investigations or biopsy unnecessarily. It is too sensitive but not specific. Good medical tests are sensitive and specific, i.e., the test is sensitive enough to catch most occurrences of the condition: and specific enough that when it is positive it is positive only for that disease, not some other condition. Some kidney specialists will not do ultrasound for that reason: they can already feel that the prostate is enlarged by feeling it on DRE.
The PSA level is also related to the size of the prostate. US would confuse the diagnosis of BPH.
US may be used to measure whether treatment for BPH is working: it will measure the decrease in size.
MRI is not used in the routine diagnosis of BPH. Once again it finds spots in the prostate that could be but probably are not cancers.
Cystoscopy: The urologist may do a csytoscopy in which the bladder is viwed directly through a scope inserted via the penis. This would be done if there was suspicion of ongoing infection or stones, or to rule out other diagnoses such as bladder cancer.
Prostate biopsy is done if other tests show a lesion which might be cancer.
IVP Intravenous pyelogram: this is a dye test to show the architecture and function of the kidneys, ureters and bladder. It would be part of investigating complications of BPH.
Urine flow measurements: Urodynamics measures how well urine is being passed. It may help in measuring response to treatment.
Blood tests for kidney function: the doctor may order a creatinine test.
Cytology involves looking for abnormal cells in urine or in biopsy specimens to rule out cancer etc.
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